Phosphatidylserine is a fat-soluble nutrient that is found in abundance in the brain and muscles. It can be synthesized by the body from two other substances, namely erythrocyte membrane and serine.
Phosphatidylserine is known to be a potent antioxidant and helps to prevent oxidative damage to cells. It also helps with neurotransmitter production, which is important for brain function, learning and memory. In dosages of 300-400mg, PS is known to positively affect ADHD.
Phosphatidylserine is also used to lower cortisol in the body. This can help with stress and physical performance. It has also been shown to improve memory and attention. It has been shown to be useful for those who have problems with mood, concentration, and sleep because of stress at work or anxiety.
Who Shouldn’t Take Phosphatidylserine?
There are some people who should not take phosphatidylserine as it can cause adverse effects on them such as stomach pain, vomiting, or diarrhea. These people include those with gastrointestinal problems such as ulcers or Crohn’s disease, those who have had abdominal surgery, or those who have gallstones.
Pregnant and lactating women should also not take phosphatidylserine. In general, taking too much phosphatidylserine can cause stomach pain or nausea. How much is too much? Anything above 300mg per day doesn’t bring additional benefits. PS works pretty fast if you take it on an empty stomach, but this might present an issue for sensitive people who should instead take it with food.
There are also certain people who should not take phosphatidylserine because of their health conditions or taking other medications. These people include those with epilepsy, depression, schizophrenia, liver disease, or those who are on blood thinners.
Forms of Phosphatidylserine
There are two forms of phosphatidylserine. One is derived from soy, which is known as soy-derived phosphatidylserine, and the other, now banned, from cow brains, known as bovine-derived phosphatidylserine.
Phosphatidylserine supplements are typically made of soybean lecithin, which is a byproduct of soybean oil production. Soybean lecithin is an emulsifier that binds to fat and water in foods and helps them stay together.
Phosphatidylserine supplements also contain other ingredients like sunflower or safflower oil, gelatin, glycerin, water, sugar, and artificial flavors.
If you’re intolerant to any of these, or if you just want to avoid them, make sure to opt for clean PS supplements, or avoid supplements altogether and get your phosphatidylserine from whole foods like eggs, organ meats, and fish.